Karla Souza (How to escape murder, 56 days) has been cast as the lead in ABC’s new show Grey’s Anatomy spin-off set in West Texas. She is the first actress to join the untitled 20th television series from executive producers Shonda Rhimes, Betsy Beers, Meg Marinis and Ellen Pompeo.
Created by Grey’s Anatomy creator Rhimes and current showrunner Marinis, the new series is described as a bold drama about a team at a rural West Texas medical center – the last chance for care before miles to nowhere.
Souza will play Carolina “Lina” Hall, a haunted and cynical doctor in her 40s who runs a medical center in a small West Texas town.
The project reunites Souza with Rhimes and Beers after the actress starred in the hit ABC series How to escape murderexecutive produced by the duo via Shondaland.
As Deadline reported last week, the new untitled Grey’s Anatomy The spin-off will be the first series to be filmed outside of Los Angeles in the United States. 23 years of franchise history. Unable to obtain a California tax credit, the offshoot, currently in pre-production, has now taken up residence in Albuquerque, New Mexico. Production is expected to begin in early 2027, around February/March, according to sources at Deadline, with a premiere during the 2027-28 season.
Shondaland has a long history of filming in California, including Seattle. Grey’s Anatomy and its previous spinoffs, Private practice And Station 19as well as two series set in Washington, D.C., ABC’s Scandal and Netflix The Residencethe ABC drama set in Philadelphia How to escape murder and the network The catch.
Souza is perhaps best known for playing Laurel alongside Viola Davis in the ABC series. How to escape murder. Most recently, she had a regular role in the Prime Video series. 56 days opposite Dove Cameron and Avan Jogia, and before that she played Marina on ABC Home economics and starred alongside Jamie Foxx in Netflix’s Day Shift. She also recently received two International Emmy Awards for producing and starring in Dive (alias La Caida) for Prime Video. Souza is replaced by Gersh, Untitled and Gang Tyre.
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