Before every Detroit Lions game in 2026, we will provide readers with an updated depth chart based on information gathered throughout the week. In Week 5, the Detroit Lions travel to the desert to take on the Arizona Cardinals.
To help you prepare for this matchup, we have a detailed Lions table that ranks all players and provides the latest news on roster changes, injury status and other relevant developments. For your viewing experience, we have listed the player numbers, in bold projected starters, and added an asterisk* after the rookies’ names.
Lions depth chart: Week 5
Interior defensive line (5)
Projected depth chart at a glance
Notes: There are 13 starters listed on defense to illustrate who is in contention for a starting role based on Lions Base and sub-package lineups.
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