The 3 public health threats that scare Michael Osterholm the most – and 4 bonus scares
Halloween gives us plenty of imaginary threats to fear: ghouls, goblins, your neighbor trying to dress like Kid Rock, and the monster under the bed (which, admittedly, makes a compelling argument for keeping your feet under the covers). Infectious…
Customer challenge
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MCT1-dependent mitochondrial lactate import supports cardiac metabolism
Human heart samples Human myocardial tissue samples were acquired from patients in the Utah Cardiac Recovery Program at the University of Utah under an approved IRB protocol (IRB-00030622). All samples were collected with informed consent from patients,…
Emotion regulation ability does not have a shared neural signature
Sheppes, G., Suri, G. & Gross, JJ Emotion regulation and psychopathology. Ann. Reverend Clin. Psychological. 11379-405 (2015). Article PubMed Google Scholar Morawetz, C. et al. Multiple large-scale neural networks underlying emotion regulation.…
Rare and common genetic variants shape single-cell immune gene expression
Cohorts Recruitment Blood samples were collected from 2,339 consenting individuals from two Australian biomedical research cohorts: the Tasmanian Ophthalmic Biobank (TOB) (ethical protocol 2020/ETH02479) and the BioHEART study cohort (ethical protocol…
T and B cells recognize neutrophil splice-derived neoantigens in lupus
Patients with SLE We obtained freshly collected blood from an adult (n= 34) SLE patients, healthy individuals (n = 20) and patients with rheumatoid arthritis (n= 15) to serve as disease control. Study participants were recruited through the University of…
How many steps do you actually need? Expert reveals ‘where you want to be’
Do you want to live longer? Go for it. You don’t necessarily need 10,000 steps a day, a misconception that actually dates back to a 60-year-old marketing campaign. “Everyone talks about 10,000 steps a day,” a workout that can last more than two…
Mayan elites buried their teeth with powerful ancestors
The Mayans liked to keep their dead close. This is how they believed they could interact with their ancestors, who had ascended to heaven to become deities. And it seems that they had a very literal interpretation of the term “near”, namely…
Scientists discover hidden reason why muscles weaken with age
Muscles naturally weaken as we age, but scientists have found that some of the changes associated with aging can actually help protect muscle cells from damage. New research reveals why aging muscles switch to a different type of muscle fiber and…
The brain liquids billions of mutant neurons at the time of our birth
By the time a baby is born, their brain has lost a large number of neurons with genetic abnormalities.Credit: Getty At the time of birth, the developing human brain mysteriously cleans itself by purging itself of large numbers of mutation-riddled…